“Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation.”

PNAS cover

AUTHORS: Liu Z, Zhang J, Sun Y, Perea-Chamblee TE, Manley JL, Rabadan R.

Proc Natl Acad Sci U S A. 2020 Apr 24. pii: 201922622. doi: 10.1073/pnas.1922622117.

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“Mutations in the RNA splicing factor SF3B1 promote tumorigenesis through MYC stabilization.”